Being a clinical trial participant takes courage. Victoria Gray, who received an investigational gene-editing therapy for sickle cell and is feeling dramatically better since, was one of the speakers at the London meeting.

CRISPR sickle cellwork in particular is very encouraging. The biggest news here is how promising somatic editing is looking on multiple fronts. I see him more as part of the past, the history here. Notably, the more specific statement on germline editing is logical but could have been even stronger. What about He Jiankui? He seems hoping for some comeback and, of course, his actions were reportedly discussed at the meeting. Here is the official word: Statement from the Organising Committee of the Third International Summit on Human Genome Editing. The statement here generally makes very good sense on the key points. What did the organizers have to say after the meeting concluded? Victoria Gray, who received an experimental CRISPR intervention for sickle cell disease and is now doing very well, was a speaker at the 2023 Human Genome Editing Summit in London.

It was good to see the agenda included quite a few new speakers. The summit addressed numerous potential clinical applications. This week the third big international human genome editing meeting took place in London. Where do things stand with potential applications of CRISPR and other gene editing technologies in patients? Overall, things are looking very positive.

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